This tutorial explores the dataset from Tengeler et al. (2020) available in the mia package.
obtained using mia::makePhyloseqFromTreeSE(Tengeler2020)
Source: R/data.R
Tengeler2020_pq.RdThis is a phyloseq version of the Tengeler2020 dataset.
Usage
data(Tengeler2020_pq)Details
Tengeler2020 includes gut microbiota profiles of 27 persons with ADHD. A standard bioinformatic and statistical analysis done to demonstrate that altered microbial composition could be a driver of altered brain structure and function and concomitant changes in the animals behavior. This was investigated by colonizing young, male, germ-free C57BL/6JOlaHsd mice with microbiota from individuals with and without ADHD.
Tengeler, A.C., Dam, S.A., Wiesmann, M. et al. Gut microbiota from persons with attention-deficit/hyperactivity disorder affects the brain in mice. Microbiome 8, 44 (2020). https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-020-00816-x